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2 Points to consider for the clinical investigation of medicinal products used in the treatment of osteoarthritis’ (CPMP/EWP/784/97)

 

3 Note for guidance on the clinical requirements for locally applied, locally acting products containing known constituents’ (CPMP/EWP/239/95)

 

4 Vaile J H, Davis P (1998) Topical NSAIDs for musculoskeletal conditions, Drugs Nov; 56 (5) 793 – 799

 

5 Zesch A (1989) Verträglichkeitsaspekte von Transdermalsystemen aus dermatologischer Sicht, Arzneim.- Forsch./Drug Res 39 (II), 11a, 1497 – 1500

 

6 Zimmermann J (1995) Upper gastrointestinal hemmorrhage associated with cutanous application of diclofenac gel.’, Am J Gastroent, Vol. 90, No. 11: 2032 – 34

 

7 Fernando AHN (1994) Renal failure after topical use of NSAIDs (letter), BMJ, 308: 533